Our goal from day one has been to provide tests for patients at all stages of cancer so they can live longer and healthier lives. We believe that to serve patients well, it is important to also act responsibly in our relationships with our employees, our communities, and the environment. This inaugural report details our current ESG initiatives and recent achievements, such as our efforts to promote diversity and inclusion across our workforce and in our clinical trials. Designating oversight responsibility for ESG matters to the Nominating and Corporate Governance Committee of the company’s Board of Directors Fostering a diverse and inclusive workforce, which was comprised of approximately 56% women and 60% non-White employees as of December 31, 2022 Recognizing the role Guardant Health can play in promoting diversity beyond its workforce by enrolling diverse patient populations for clinical trials and partnering with local communities to increase diverse enrollment Developing processes to measure important sustainability-related data across Guardant Health’s global operations.